Point and click pixel art space trading game with turn based combat and that's pretty unique, can't think of anything with has combined the two genres. Although their was The Last Dynasty and the inca games but I think they were more space shooter/ adventure games. Anyhow website here http://www.massivegalaxy.com/ with nothing on it and the Steam page here https://store.steampowered.com/app/785050/Massive_Galaxy/ with a bit on it. Really like the look of this and I'm going to put it on my wishlist.

From Steam

Massive Galaxy combines classic point and click gameplay with space trading, turn-based combat and galactic exploration in an immersive pixel-art worldTravel to distant planets full of rich and diverse cultures, investigate technologically advanced space habitats and uncover the history and lore of ancient civilizations.Become a space-trader seeking to turn a profit by buying and selling goods throughout the galaxy.
Undertake routine missions or embark on ethically questionable jobs for a quick-buck.Trade in densely populated cities, harsh wastelands and discover rare alien artifacts and ships.

 

Features
Point and click narrative adventure with a highly stylized retro-vibe
Dozens of planets, space stations and habitats to explore
Trade and work as a smuggler, courier, spy or just be a space-pirate!
Meet several space faring alien civilizations, explore the fauna and flora of uncharted planets
Synth-laden soundtrack
System Requirements
Minimum:
OS: Windows 7
Processor: 1.7 GHz Dual Core
Memory: 4 GB RAM
Graphics: Intel HD 3000
DirectX: Version 10
Storage: 300 MB available space