Yes good selection of games there Solace, to your list I would add Homeworld III, Elite IV, Freelancer II, Nexus The Jupiter Incident II, Thief IV and System Shock III. Only rumours so far concerning the development status or even the existence of these games so far sadly. As for Total Annihilation II, The Supreme Commander games were more or less just that.

Definitely Homeworld 3 and Nexus 2, for me.

1 game, and 1 game only. It nearly brings a tear to my eye knowing how great it could have been.

Van Buren

The true sequel to the fallout games. Actually based on the original fallouts, in overhead 3d.

The game was 90% complete I believe.

I see Putty Squad is finally getting a release, sadly not on the Amiga but the Iphone.

Definitely Dungeon Keeper 3!! I had a blast playing the first two! Much more fun than Overlord.

System Shock 3 would have been great. 2 was really cool (and maybe a little creepy 😀 ).

I think they should have continued Sin Episodes, or at least one more to create a satisfying conclusion. They kinda left it up in the air with 1.

Definitely System Shock III. Shock 1 and 2 were great, best sci-fi horror games with great characters and story. Such games like Dead Space or Doom 3 can never catch up with the great atmosphere of the shock games.

Wing Commander 6 of course... R.I.P.

Privateer III, Privateer Online. The Babaylon 5 game(But it's great that there is a really good Fan game to Babylon 5).

A second Planescape Torment or a third Baldurs Gate would be great, but i don't know if they were cancelled because i think they never planned a sequel to this games.

I can't believe none of you suckas has mentioned Freespace 3 (since we've veered into sequels we'd like to see rather than actual games that were canceled). 😉

Freelancer 2 need i say anymore 🙄

Freelancer 2

From what I've heard, Microsoft ate Digital Anvil, so it wouldn't be easy for it to be made now.

I was going to say Huxley, but it still seems to be shambling around.

http://pc.ign.com/articles/111/1116725p1.html